منابع مشابه
Non-Proteinuric Diabetic Nephropathy
Diabetic nephropathy patients traditionally show significant macroalbuminuria prior to the development of renal impairment. However, this clinical paradigm has recently been questioned. Epidemiological surveys confirm that chronic kidney disease (CKD) diagnosed by a low glomerular filtration rate (GFR) is more common in diabetic patients than in the non-diabetic population but a low number of p...
متن کاملDiabetic Nephropathy and its two phenotypes: the proteinuric and non-proteinuric
The prevalence of type 2 diabetes mellitus (T2DM) is steadily increasing, mostly due to a combination of obesity, urbanization, and ageing population.1,2 In parallel, the prevalence of its macrovascular and microvascular complications, such as diabetic nephropathy (DN), which occurs in 20 to 40% of type 2 diabetic patients, has risen.3,4 Despite efforts made to slow the progression of DN, this ...
متن کاملDiabetic retinopathy is a poor predictor of type of nephropathy in proteinuric type 2 diabetic patients.
BACKGROUND Both diabetic nephropathy (DN) and nondiabetic nephropathy (NDN) are reported to occur in patients with type 2 diabetes mellitus (DM). The precise diagnosis of the type of nephropathy has obvious clinical and prognostic implication. The aim of the study was to evaluate the histologic spectrum of nephropathy in proteinuric type 2 diabetic patients and to find the correlation between t...
متن کاملNon-diabetic nephropathy in diabetics
In previous studies, most researchers tried to find predictors to differentiate nondiabetic renal diseases (NDRDs) from diabetic nephropathy in diabetic patients. As the chronology is variable, it is not easy to predict NDRDs in patients with diabetes, especially type 2 diabetes. Absence of retinopathy, short duration of diabetes, presence of hematuria, and heavy proteinuria in preserved renal ...
متن کاملHow Is Proteinuric Diabetic Nephropathy Caused by Disturbed Proteostasis and Autophagy in Podocytes?
Progression of diabetic nephropathy (DN) is commonly defined by an increase in albuminuria from normoalbuminuria to microalbuminuria and from microalbuminuria to macroalbuminuria. Although many therapeutic interventions, including reducing hyperglycemia and intraglomerular pressure, have been shown to slow down the progression of DN, many patients still develop end-stage renal disease. A major ...
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ژورنال
عنوان ژورنال: Journal of Clinical Medicine
سال: 2015
ISSN: 2077-0383
DOI: 10.3390/jcm4091761